Pill pockets
Best for pets who are food-motivated and not especially suspicious. A good pocket fully encloses the pill in something strong-smelling enough to mask it. It fails when a pet is a careful eater who detects the pill and works it out, or spits the whole thing back out.
Syringe (liquid medication)
Works well for pets who won't take pills at all, and for medications that come in a liquid formulation. It's more precise for dosing than crushing, but takes practice to do smoothly, and an anxious first attempt can make a pet harder to syringe next time. Go slowly, and never syringe faster than your pet can swallow.
Crushed into food
Works best mixed into a small, separate portion of strong-smelling wet food, not stirred into a full meal where it can be avoided or where your pet may eat around it. Not every medication can be crushed safely or still works the same way once crushed, so this one specifically needs checking with a vet or pharmacist first.
What we've actually settled on
For Angel, it's a mix: some medications in pockets, one that has to be given more precisely by syringe. There's no single method that would work for everything she takes, and that's fairly normal for multi-medication routines, see building a routine you won't forget for how the rest of it fits together.
The one constant, whatever the method
Whichever way a dose actually goes in, Halo logs it the same way, a tap the moment it's done, so switching methods for a difficult day never means losing track of what's actually been given.